HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Szakacs, J. E. Articles by Szakacs, J. G. Search for Related Content PubMed Articles by Szakacs, J. E. Articles by Szakacs, J. G.

Potter’s Pathology of the Fetus, Infant and Child, 2nd Edition

Editor: Enid Gilbert-Barness

Departments of Pathology, Cell Biology, Pediatrics, and Obstetrics and Gynecology, University of South Florida College of Medicine and Tampa General Hospital, Tampa Florida

ISBN 9780323034036; Mosby Elsevier, Philadelphia, 2007, 2 vol, pp 2444 hardcover, 2500 illustrations, mostly in color, with CD-ROM, $399.00

The latest edition of Potter’s Pathology of the Fetus, Infant, and Child, the pre-eminent textbook of pediatric pathology, continues in the tradition of excellence since the first edition in 1997 under the editorship of Dr. Enid Gilbert-Barness.

The explosive growth in molecular biology and new diagnostic techniques has impacted all fields of medicine, but especially the area of fetal-pediatric pathology. This new edition, following 10 years after the previous one, incorporates pertinent new information with specific and detailed explanations of molecular mechanisms of growth, development, and genetics based on nucleic acid technology.

To accommodate the massive increase in knowledge, six new chapters have been added. All chapters have been updated and enriched with new information. The text is comprehensive, concise, and reader-friendly. The clarity of the text is enhanced by over 2500 color illustrations, tables, and line drawings of high quality.

In order to cover multiple specialized fields the Editor was assisted by two associate editors, Raj K. Kapur and Lac L. Oligny, an assistant editor, Joseph R. Siebert, and 43 contributing editors.

In the two handsome volumes the chapters are grouped into four parts. Part I: "Pathogenesis of Fetal and Infantile Disorders" includes 13 chapters in a logical sequence. Each chapter is complete in itself with its references. Chapter 1, "Mechanisms of Development and Growth, Molecular Genetics," is an elegant presentation of molecular concepts applicable to the exploration of birth defects and oncogenesis. The discussion extends from basic genetics to the frontiers of developmental pathology, genomics, and mitochondrial and maternal effect mutation.

Questions on cytoplasmic inheritance raised in 1949 by Prof. G. Cotronei in his inaugural address to the Academia dei Lincei can now be answered through molecular developmental genetics, as is discussed in "Novel Inheritance Mechanisms" by Wilson and Oligny. This chapter includes a glossary of genetic and developmental terms and references with commentary.

In the following chapters John M. Opitz offers a broad scientific background on the pathogenesis of birth defects and an analysis of developmental pathology. Causes of abortion, fetal and neonatal death, infections, nutritional and metabolic diseases, and complications of perinatal care are some of the other topics in Part I.

Part II: "Examination of the Fetus and Infant" introduces practical considerations for clinicians and pathologists. It covers the topics of prenatal diagnosis, sudden death in infants, and specialized autopsy procedures. New in this edition is a chapter on the use of auxiliary tests in perinatal pathology. An algorithm is presented to help pathologists at the gross examination to collect and preserve tissue specimens that are suitable and adequate for testing in most types of perinatal cases. The tests range from traditional cytogenetics to fluorescence-in-situ-hybridization, cytogenetic breakage studies, flow cytometry, and microbiological and viral cultures.

Part III: "Major Anomalies of External Anatomy or In-Situ Relationships" is extended in this edition by two new chapters, "Disorders of the Anterior Thoracic and Abdominal Walls," and "Back and Perineum." The chapter on craniofacial abnormalities is updated by M. Michael Cohen Jr. The complex embryology of the craniofacial region is analyzed in terms of genetic and molecular correlates.

Part IV: "Systemic Pathology" occupies more than 1200 pages of volume 2. The Editor and contributors present authoritative treatises based on their personal experiences in tens of thousands of autopsies and biopsies. System by system, the chapters begin with a general overview and incorporate up-to-date genetic and molecular information. Organ and tissue pathology is extensively illustrated. The chapter on classification of congenital heart diseases is a true text/atlas. All body systems as well as tumors and overgrowth syndromes of the fetus and infant have their own chapters.

This textbook is not only intellectually satisfying but also fundamental to the daily practice of pediatric pathology. The scope and breadth of information in this work are invaluable to pathologists, obstetricians, and pediatricians. It will also appeal to geneticists and clinical scientists. The extensive index and the included CD-ROM make Enid Gilbert-Barness’s second edition of this great handbook easy to use and a favorite reference in the pathology laboratory and in the clinic.

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Szakacs, J. E. Articles by Szakacs, J. G. Search for Related Content PubMed Articles by Szakacs, J. E. Articles by Szakacs, J. G.