Annals of Clinical and Laboratory Science, Vol 7, Issue 1, 88-92
Copyright © 1977 by Association of Clinical Scientists
Inhibitory effects of ATP on platelet aggregation: cation interaction and shape change
TY Wang,
CV Hussey,
and
JC Garancis
Adenosine triphosphate (ATP) has more than one effect in its inhibition of platelet aggregation. In addition to its direct competition with adenosine diphosphate (ADP), ATP may suppress the aggregation mediated via a cation interaction and a restoration of platelet shape.