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Annals of Clinical and Laboratory Science, Vol 5, Issue 2, 115-122
Copyright © 1975 by Association of Clinical Scientists

Articles

McArdle's disease: a review

MM Lubran

The clinical features of McArdle's disease (inherited deficiency of skeletal muscle phosphorylase) and the histological and biochemical changes are described. Their possible causes are discussed in the light of recent knowledge of the biochemistry of muscular contraction. Diagnostic tests are detailed. Attention is drawn to the possibility that the disease may be due to primary defect of motoneurons.


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Home page
 J Child NeurolHome page
J. M. Milstein, T. M. Herron, and J. E. Haas
Fatal Infantile Muscle Phosphorylase Deficiency
J Child Neurol, July 1, 1989; 4(3): 186 - 188.
[Abstract] [PDF]


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Copyright © 1975 by the Association of Clinical Scientists.