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Annals of Clinical & Laboratory Science 38:380-385 (2008)
© 2008 Association of Clinical Scientists

Case Report and Literature Review

Acute Pneumonitis and Alveolar Hemorrhage after Subcutaneous Injection of Liquid Silicone

Rupen Parikh1, Karim Karim2, Nalini Parikh3, Paul Han4, Joseph Daoko1 and Fayez E. Shamoon1
1 Departments of Cardiology, 2 Internal Medicine and 3 Pathology, School of Graduate Medical Education, Seton Hall University and St.Michael’s Medical Center, Newark, New Jersey; 4 Department of Pulmonary Disease, Holy Name Hospital, Teaneck, New Jersey

Address correspondence to Karim Karim, M.D., Primary Care Ctr, St. Michael’s Medical Center, 268 Dr. M. L. King Jr Bvld, Newark, NJ 07102, USA; tel 973 877 5086; fax 973 877 2718; e-mail karimkarim73{at}hotmail.com.

Lay (non-medical) injection of silicone may lead to serious clinical consequences. Most reports of illicit cosmetic procedures have dealt with failed, lay attempts at breast augmentation. Although these procedures have resulted in severe pneumonitis and alveolar hemorrhage, reports of similar complication after lay attempts at buttock augmentation have been sparse. We describe one of these rare cases and review the literature on clinicopathologic sequelae of lay attempts at cosmetic procedures using commercially available silicone preparations.

Keywords: silicone pneumonitis, silicone embolism, alveolar hemorrhage






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