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Annals of Clinical & Laboratory Science 37:362-365 (2007)
© 2007 Association of Clinical Scientists

Case Report

IgE-Mediated Hypersensitivity After Ibuprofen Administration

Martin H. Bluth1,2, Pedro Beleza4, Feryal Hajee2, Maria José Jordão4, José Figueiredo4, Fatima Almeida4 and Tamar Smith-Norowitz3
1 Departments of Surgery and Pathology, 2 Medicine, and 3 Pediatrics, SUNY Downstate Medical Center, Brooklyn, New York, USA; 4 Department of Neurology, São Marcos Hospital, Braga, Portugal

Address correspondence to Martin H. Bluth, M.D., Ph.D., SUNY Downstate Medical Center, Box 40, 450 Clarkson Avenue, Brooklyn, NY 11203, USA; tel 718 270 6772; fax 718 221 6132; e-mail martin.bluth{at}downstate.edu.

Although many immunoglobulin-related drug sensitivities have been described, there is a paucity of reports regarding IgE-related drug sensitivities. Here we describe a case of a patient who demonstrated IgE-mediated sensitivity to ibuprofen.

Keywords: aseptic meningitis, hypersensitivity, ibuprofen, serum IgE






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