Advances in the analysis of cerebrospinal fluid

The laboratory examination of cerebrospinal fluid (CSF) continues to play an important role in the clinical diagnosis and treatment of various disorders of the central nervous system (CNS). The major conditions currently include, as they have in the past, infectious diseases, neoplastic processes, multiple sclerosis, other demyelinating disorders, and intracerebral hemorrhage. Recent publications suggest a variety of new laboratory tests that may be useful in the evaluation of patients with both primary and metastatic malignancies, Alzheimer's disease, Creutzfeld-Jacob disease, global ischemia, various psychiatric disorders, CSF otorrhea and rhinorrhea, and in the differential diagnosis of cortical vs lacunar stroke, among others. Examples of these recent developments and their possible clinical usefulness are discussed.

This article has been cited by other articles:

				T. Gorogh, P. Rudolph, J. E. Meyer, J. A. Werner, B. M. Lippert, and S. Maune Separation of {beta}2-Transferrin by Denaturing Gel Electrophoresis to Detect Cerebrospinal Fluid in Ear and Nasal Fluids Clin. Chem., September 1, 2005; 51(9): 1704 - 1710. [Abstract] [Full Text] [PDF]

				Y. Goldshmit, S. Erlich, and R. Pinkas-Kramarski Neuregulin Rescues PC12-ErbB4 Cells from Cell Death Induced by H2O2. REGULATION OF REACTIVE OXYGEN SPECIES LEVELS BY PHOSPHATIDYLINOSITOL 3-KINASE J. Biol. Chem., November 30, 2001; 276(49): 46379 - 46385. [Abstract] [Full Text] [PDF]