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Annals of Clinical and Laboratory Science, Vol 19, Issue 3, 184-189
Copyright © 1989 by Association of Clinical Scientists

Articles

Von Willebrand factor and von Willebrand's disease: a complex protein and a complex disease

RD Bona

Von Willebrand factor is a complex protein which is important in several ways for normal hemostasis. Von Willebrand's disease results when there is either a quantitative or qualitative disorder of von Willebrand factor. In this review, the structure and function of von Willebrand factor are discussed. Additionally, the current laboratory and clinical classification of von Willebrand's disease and closely related variants are outlined.




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Copyright © 1989 by the Association of Clinical Scientists.