Annals of Clinical and Laboratory Science, Vol 18, Issue 1, 53-57
Copyright © 1988 by Association of Clinical Scientists
Current status of radioligand antibodies in the treatment of malignancy
AW Maners,
MM Sanders,
and
AA Pappas
Monoclonal anti-tumor antibodies labeled with a radioactive moiety present an exciting new approach to cancer therapy. With the advent of hybridoma technology, monoclonal antibodies can now be produced in quantity. Indeed, antibodies against tumor-related and tumor-specific antigens have been produced, labeled with a radioactive substance, and used therapeutically. The rationale for this therapeutic approach and the results of human clinical trials will be reported herein.