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Annals of Clinical and Laboratory Science, Vol 17, Issue 5, 339-344
Copyright © 1987 by Association of Clinical Scientists

Articles

Platelet-directed antibody in the serum of patients with primary thrombotic thrombocytopenic purpura

J Lazarchick, SL Graddick, SA Hall, and PV Genco

Utilizing two platelet antibody assay systems, flow cytometric analysis and a microcytotoxicity assay, it was possible to demonstrate for the first time platelet-directed antibody in the sera of three of six patients with primary thrombotic thrombocytopenic purpura. These results lend support for an immune-mediated pathologic process in some patients with this disorder.




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Copyright © 1987 by the Association of Clinical Scientists.