Annals of Clinical and Laboratory Science, Vol 17, Issue 1, 8-13
Copyright © 1987 by Association of Clinical Scientists
The use of deoxyribonucleic acid probes in the evaluation of hemophilia
PL Howard
The use of deoxyribonucleic acid (DNA) probes is an important addition to existing laboratory methods for detection of carriers of hemophilia A and B. Both intragenic probes and probes directed at DNA restriction fragment length polymorphisms linked to the disease locus are now available. This technology will aid in genetic counseling of affected families and will impact upon clinical laboratory science in the near future.