Annals of Clinical and Laboratory Science, Vol 17, Issue 1, 60-62
Copyright © 1987 by Association of Clinical Scientists
Spontaneous formation of an anti-S alloantibody in association with mixed connective tissue disease
SH Pepkowitz,
J Lazarchick,
and
BW Usher
A spontaneous anti-S alloantibody developed without prior transfusion in a 33-year-old male with mixed connective tissue disease. It was detectable by indirect antiglobulin testing using anti-IgG specific, as well as polyspecific anti-human globulin. All previously reported naturally occurring anti-S antibodies had been cold reactive agglutinins, presumably IgMs.