Annals of Clinical and Laboratory Science, Vol 16, Issue 3, 241-244
Copyright © 1986 by Association of Clinical Scientists
Appearance of light chain disease in serum electrophoresis. Report of 11 cases
ML Salkie
Over a five year period, 13 cases of light chain disease were identified. Ten patients had abnormalities noted on serum immunoelectrophoresis with anti-whole-human antiserum. Eight of these ten patients had a distinctive rainbow-like arc between the IgG and transferrin arcs, and two had splitting of the IgG arc. These patterns may be seen in the presence of free light chains; their recognition should lead to further studies with appropriate antisera.