Annals of Clinical and Laboratory Science, Vol 16, Issue 3, 189-197
Copyright © 1986 by Association of Clinical Scientists
Modified creatine kinase-MB plots as a tool to detect perioperative myocardial infarction. Evaluation of sensitivity and specificity as compared with electrocardiographic changes
G Jambroes,
JA Gimpel,
JF Hitchcock,
EO Robles de Medina,
and
AH Maas
Based on electrocardiographic criteria, coronary artery bypass grafting patients were divided into two groups, one with and one without perioperative myocardial infarction. Serial total-creatine kinase activity did not discriminate between the two groups; however, serial creatine kinase-MB activity showed a consistent difference. Patients with perioperative myocardial infarction showed an increase, whereas patients without perioperative myocardial infarction showed a decrease during the postoperative period. The creatine kinase-MB plots showed a sensitivity of 0.92 and a specificity of 0.98 as compared with the electrocardiograms.