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Annals of Clinical and Laboratory Science, Vol 13, Issue 5, 400-406
Copyright © 1983 by Association of Clinical Scientists

Articles

Retinoic acid binding protein in human and experimental pancreatic carcinomas in hamsters

M Brandes, MS Gesell, H Ueda, JC Millan, RM Quinlan, C Ernst, WF Sindelar, CC Kurman, S Harris, and D Brandes

Cytoplasmic retinoic acid binding protein (cRABP) is present in human fetal pancreas and becomes nondetectable in the normal adult pancreas. The binding protein for retinoic acid becomes apparent again in pancreatic cancer. Similar fluctuations in the content of cRABP occur in the hamster. The binding protein is undetectable in the normal adult hamster pancreas, while it was detected in several transplantable adenocarcinomas in the Syrian golden hamster.




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Copyright © 1983 by the Association of Clinical Scientists.