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Annals of Clinical and Laboratory Science, Vol 11, Issue 3, 262-268
Copyright © 1981 by Association of Clinical Scientists

Articles

In vitro methods for detection of circulating immune complexes

R Blackstock

The possible pathologic consequences of the presence of circulating immune complexes in certain disease states has caused considerable attention to be given to the development of laboratory procedures capable of quantitatively measuring the presence of immune complexes in serum. Many assays are available which utilize differing properties of immune complexes for their detection. Examples of assays which depend on different biologic properties of circulating immune complexes are presented and discussed. Included are the Raji cell assay, Clq binding assay, inhibition of rheumatoid agglutination, and nephelometric assays for determination of circulating immune complexes.




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Copyright © 1981 by the Association of Clinical Scientists.