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Annals of Clinical and Laboratory Science, Vol 10, Issue 6, 515-517
Copyright © 1980 by Association of Clinical Scientists

Articles

Megaloblastic, dyserythropoietic anemia following arsenic ingestion

BB Lerman, N Ali, and D Green

Following acute arsenic ingestion, a 35 year old woman experienced multiple organ failure, including renal and respiratory insufficiency, toxic hepatitis, peripheral neuropathy, and encephalopathy. In addition, she developed an anemia; the bone marrow showed a striking dyserythropoiesis with megaloblastic features. Her recovery was heralded by normalization of the bone marrow morphology, followed by improvement in all other organ dysfunction except for the peripheral neuropathy. Arsenic poisoning is a cause of megaloblastic anemia; early hematologic recovery suggests favorable prognosis.


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R N Ratnaike
Acute and chronic arsenic toxicity
Postgrad. Med. J., July 1, 2003; 79(933): 391 - 396.
[Abstract] [Full Text] [PDF]


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